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Agent skills

Reusable instructions for compatible AI agents.

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Agent skill

HLA Typing for Clinical Applications

Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or HIBAG imputation. Use when typing for HSCT, solid-organ transplant, neoantigen prediction, PGx screening (B*57:01, B*15:0...

ClaudeCodexOpenClawHealthcare & Life Sciences
GPTomics1,232
Agent skill

MeRIP-seq End-to-End Pipeline

Orchestrates an end-to-end MeRIP-seq / m6A-seq analysis from raw FASTQ to differential m6A peak calls and metagene plots, chaining fastp adapter trimming, STAR splice-aware genome alignment (NO deduplication for non-UMI MeRIP), deepTools replicate-concordance + IP-enrichment QC, PreSeq saturation...

ClaudeCodexOpenClawData & Analytics
GPTomics1,232
Agent skill

bedGraph Handling

Generates, normalizes, and converts bedGraph signal tracks (4-column chrom/start/end/value, 0-based half-open) with bedtools genomecov, deepTools bamCoverage/bamCompare/bigwigCompare, bedtools unionbedg, and UCSC bedGraphToBigWig. Covers why a raw coverage bedGraph is not comparable across sample...

ClaudeCodexOpenClawData & Analytics
GPTomics1,232
Agent skill

Coverage Analysis

Computes and interprets sequencing read depth and coverage over a genome, windows, or target regions with mosdepth (windowed depth, cumulative distribution, --quantize callable BEDs), bedtools genomecov/coverage (bedGraph tracks, per-target stats), samtools depth/coverage (per-base depth, per-con...

ClaudeCodexOpenClawData & Analytics
GPTomics1,232
Agent skill

ATAC-seq Pipeline

End-to-end ATAC-seq workflow from FASTQ files to differential accessibility and TF footprinting. Covers alignment, peak calling with MACS3, QC metrics, and optional TOBIAS footprinting. Use when running end-to-end ATAC-seq analysis from FASTQ to differential accessibility.

ClaudeCodexOpenClawData & Analytics
GPTomics1,232
Agent skill

Reference Operations

Generate consensus sequences and manage reference files using samtools. Use when creating consensus from alignments, indexing references, or creating sequence dictionaries.

ClaudeCodexOpenClawData & Analytics
GPTomics1,232
Agent skill

Consensus Peakset Construction

Build a differential-ready consensus peakset from per-replicate ATAC-seq peaks using iterative overlap removal, fixed-width re-centering, and majority-rule overlap. Use when generating a stable peak coordinate system for downstream differential accessibility, ML feature engineering, cross-sample ...

ClaudeCodexOpenClawData & Analytics
GPTomics1,232
Agent skill

Metagenome Assembly

Assembles microbial-community sequencing into metagenome-assembled genomes (MAGs) with metaFlye (ONT), metaSPAdes/MEGAHIT (Illumina), and hifiasm-meta/metaMDBG (PacBio HiFi), then recovers genomes via multi-binner consolidation (MetaBAT2, MaxBin2, CONCOCT, SemiBin2, VAMB -> DAS_Tool) and QCs them...

ClaudeCodexOpenClawData & Analytics
GPTomics1,232
Agent skill

CLIP-seq Quality Control

Comprehensive quality control for CLIP-seq libraries (eCLIP, iCLIP, iCLIP2, PAR-CLIP) covering library complexity (preseq), FRiP, IDR replicate reproducibility, read-distribution metagene, SMInput vs IgG control rationale, rRNA / snoRNA contamination, fragment-length distribution, and ENCODE-comp...

ClaudeCodexOpenClawData & Analytics
GPTomics1,232
Agent skill

BAM Statistics

Generate alignment statistics using samtools flagstat, stats, depth, coverage, and mosdepth. Use when assessing alignment quality, calculating coverage, or generating QC reports.

ClaudeCodexOpenClawData & Analytics
GPTomics1,232
Agent skill

Eukaryotic Gene Prediction

Predicts protein-coding gene structures (exons, introns, UTRs) in eukaryotic genomes with BRAKER3 (RNA-seq + protein evidence), BRAKER1/BRAKER2, GALBA (protein-only), Funannotate (fungi), GeMoMa (homology projection), or Helixer/Tiberius (deep-learning ab initio). Covers the evidence-first tool d...

ClaudeCodexOpenClawData & Analytics
GPTomics1,232

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